STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHHDesert hedgehog signaling molecule. (377 aa)    
Predicted Functional Partners:
CDON
Cell adhesion associated, oncogene regulated.
    
 0.993
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.993
HHIP
Hedgehog interacting protein.
    
 0.990
PTCH1
Patched 1.
   
 0.990
PTCH2
Patched 2.
   
 0.983
DISP1
Dispatched RND transporter family member 1.
   
 0.980
SMO
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.970
GAS1
Growth arrest specific 1.
    
 0.967
GPC5
Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.932
DISP2
Dispatched RND transporter family member 2.
   
 0.926
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.