STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MROH8Maestro heat like repeat family member 8. (1035 aa)    
Predicted Functional Partners:
LOXHD1
Lipoxygenase homology domains 1.
      
 0.802
PTPRQ
Protein tyrosine phosphatase receptor type Q.
      
 0.707
UBE3B
Ubiquitin protein ligase E3B.
      
 0.677
NFS1
Aminotran_5 domain-containing protein.
      
 0.668
PLA2G1B
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family.
      
 0.559
KPNB1
Karyopherin subunit beta 1.
      
 0.550
MID2
Midline 2.
      
 0.523
SLC33A1
Solute carrier family 33 member 1.
   
  
 0.517
XPO1
Exportin 1.
      
 0.515
POLR2C
RNA polymerase II subunit C.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.