STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MROH8Maestro heat like repeat family member 8. (1035 aa)    
Predicted Functional Partners:
LOXHD1
Lipoxygenase homology domains 1.
      
 0.811
PTPRQ
Protein tyrosine phosphatase receptor type Q.
      
 0.771
MID2
Midline 2.
   
  
 0.495
PLAT
Uncharacterized protein.
      
 0.482
PLA2G1B
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family.
      
 0.470
KPNB1
Karyopherin subunit beta 1.
      
 0.469
LRRC52
Leucine rich repeat containing 52.
      
 0.467
C3AR1
Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.
  
     0.448
OGFOD3
2-oxoglutarate and iron dependent oxygenase domain containing 3.
      
 0.426
ART5
NAD(P)(+)--arginine ADP-ribosyltransferase.
  
     0.411
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]