TET3 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TET3

Tet methylcytosine dioxygenase 3. (1795 aa)

Predicted Functional Partners:

DNMT3A

0.865

DNMT1

0.858

TDG

0.746

OGT

0.704

DNMT3L

0.643

EPC1

0.614

TET2

0.614

NANOG

0.608

ARID4B

0.595

PRMT5

0.581

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4B	EPC1	ENSCAFP00000016861	ENSCAFP00000006083	AT-rich interaction domain 4B.	Enhancer of polycomb homolog.	0.573
ARID4B	OGT	ENSCAFP00000016861	ENSCAFP00000025249	AT-rich interaction domain 4B.	O-linked N-acetylglucosamine (GlcNAc) transferase.	0.508
ARID4B	TET2	ENSCAFP00000016861	ENSCAFP00000015986	AT-rich interaction domain 4B.	Tet methylcytosine dioxygenase 2.	0.741
ARID4B	TET3	ENSCAFP00000016861	ENSCAFP00000012834	AT-rich interaction domain 4B.	Tet methylcytosine dioxygenase 3.	0.595
DNMT1	DNMT3A	ENSCAFP00000026412	ENSCAFP00000006185	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.999
DNMT1	DNMT3L	ENSCAFP00000026412	ENSCAFP00000015781	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Uncharacterized protein.	0.873
DNMT1	NANOG	ENSCAFP00000026412	ENSCAFP00000020496	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Homeobox domain-containing protein.	0.417
DNMT1	PRMT5	ENSCAFP00000026412	ENSCAFP00000016548	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.440
DNMT1	TDG	ENSCAFP00000026412	ENSCAFP00000011067	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Thymine DNA glycosylase.	0.655
DNMT1	TET2	ENSCAFP00000026412	ENSCAFP00000015986	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Tet methylcytosine dioxygenase 2.	0.836
DNMT1	TET3	ENSCAFP00000026412	ENSCAFP00000012834	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Tet methylcytosine dioxygenase 3.	0.858
DNMT3A	DNMT1	ENSCAFP00000006185	ENSCAFP00000026412	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.999
DNMT3A	DNMT3L	ENSCAFP00000006185	ENSCAFP00000015781	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Uncharacterized protein.	0.966
DNMT3A	NANOG	ENSCAFP00000006185	ENSCAFP00000020496	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Homeobox domain-containing protein.	0.469
DNMT3A	PRMT5	ENSCAFP00000006185	ENSCAFP00000016548	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.	0.635
DNMT3A	TDG	ENSCAFP00000006185	ENSCAFP00000011067	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Thymine DNA glycosylase.	0.568
DNMT3A	TET2	ENSCAFP00000006185	ENSCAFP00000015986	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Tet methylcytosine dioxygenase 2.	0.863
DNMT3A	TET3	ENSCAFP00000006185	ENSCAFP00000012834	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Tet methylcytosine dioxygenase 3.	0.865
DNMT3L	DNMT1	ENSCAFP00000015781	ENSCAFP00000026412	Uncharacterized protein.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.873
DNMT3L	DNMT3A	ENSCAFP00000015781	ENSCAFP00000006185	Uncharacterized protein.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.966