STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL2BPADP ribosylation factor like GTPase 2 binding protein. (163 aa)    
Predicted Functional Partners:
ENSCAFP00000055826
Uncharacterized protein.
   
 0.910
ARL2
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
   
 
 0.718
RSPRY1
Ring finger and SPRY domain containing 1.
 
    
 0.566
PLA2G1B
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family.
      
 0.562
C29H8orf37
Chromosome 29 C8orf37 homolog.
      
 0.547
TTC8
Tetratricopeptide repeat domain 8 isoform 1.
   
  
 0.529
RP1L1
RP1 like 1.
      
 0.523
RPGR
X-linked retinitis pigmentosa GTPase regulator; Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. May be involved in microtubule organization and regulation of transport in primary cilia. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes.
      
 0.516
SLC25A4
Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  0.511
IL4R
Interleukin 4 receptor.
   
  
 0.488
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.