STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC65Coiled-coil domain containing 65. (497 aa)    
Predicted Functional Partners:
DNAI1
Dynein axonemal intermediate chain 1.
   
  
 0.954
GAA
Glucosidase alpha, acid.
   
 
 0.861
CCDC83
Coiled-coil domain containing 83.
  
    0.852
CCDC39
Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly.
   
 
 0.845
LRRC6
Leucine rich repeat containing 6.
   
  
 0.842
EFCAB6
EF-hand calcium binding domain 6.
   
   0.833
CFAP99
Cilia and flagella associated protein 99.
   
   0.821
DNAH10
Dynein axonemal heavy chain 10.
   
  
 0.819
DNAH11
Dynein axonemal heavy chain 11.
   
  
 0.815
ANKEF1
Ankyrin repeat and EF-hand domain containing 1.
   
    0.805
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.