STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRTAP8-1Keratin associated protein 8-1. (63 aa)    
Predicted Functional Partners:
KRTAP7-1
Keratin associated protein 7-1.
   
  
 0.958
KRTAP24-1
Keratin associated protein 24-1.
   
 
 0.840
ENSCAFP00000060355
Uncharacterized protein.
   
 
 0.832
KRTAP3-1
Keratin associated protein 3-1.
   
 
 0.764
LOC100686522
Uncharacterized protein.
   
  
 0.729
KRTDAP
Keratinocyte differentiation-associated protein; May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis (By similarity).
      
 0.709
LOC102151831-2
4Fe-4S ferredoxin-type domain-containing protein.
   
 
 0.675
HAMP
Hepcidin; Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity (By similarity). Belongs to the hepcidin family.
   
    0.666
H2BC1
Histone H2B; Belongs to the histone H2B family.
   
    0.666
OR51A7
Olfactory receptor family 51 subfamily A member 7.
   
    0.660
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.