STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPZ1Spermatogenic leucine zipper 1. (367 aa)    
Predicted Functional Partners:
PREB
Prolactin regulatory element binding.
    
 
 0.651
PATZ1
POZ/BTB and AT hook containing zinc finger 1.
    
 
 0.631
SPATA4
Spermatogenesis associated 4.
   
 
 0.613
PLAAT5
Phospholipase A and acyltransferase 5.
      
 0.589
PLA2G7
Platelet-activating factor acetylhydrolase; Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids; Belongs to the AB hydrolase superfamily. Lipase family.
      
 0.585
ACTL7B
Actin like 7B; Belongs to the actin family.
   
 0.560
KLHDC3
Kelch domain containing 3.
      
 0.543
MEA1
Male-enhanced antigen 1.
      
 0.534
TCHHL1
Trichohyalin like 1.
  
 
  0.531
SFI1
SFI1 centrin binding protein.
      
 0.522
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]