STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL2Kelch like family member 2. (587 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.941
AOC3
Amine oxidase copper containing 3.
    
 
 0.906
PCNP
PEST proteolytic signal containing nuclear protein.
      
 0.858
KLHL12
Adiponectin receptor 1.
    
   0.834
RBX1
Ring-box 1.
    
 0.831
TULP4
Tubby like protein 4; Belongs to the TUB family.
      
 0.810
KLHL3
Kelch like family member 3.
    
   0.809
UCK1
Uridine-cytidine kinase 1.
   
 
 0.805
DCTN1
Dynactin subunit 1.
    
  0.778
KEAP1
Kelch like ECH associated protein 1.
    
   0.770
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.