STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNT1Cyclin T1; Belongs to the cyclin family. (725 aa)    
Predicted Functional Partners:
AFF4
AF4/FMR2 family member 4.
   
 0.999
CDK9
Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.
   
 0.999
CCNT2
Cyclin T2; Belongs to the cyclin family.
    
0.998
BRD4
Bromodomain containing 4.
   
 
 0.980
CDK12
Cyclin dependent kinase 12.
   
 0.977
CCNK
Cyclin K; Belongs to the cyclin family.
   
 
0.967
CDK13
Cyclin dependent kinase 13.
   
 0.967
AFF1
AF4/FMR2 family member 1.
   
 0.957
LARP7
La ribonucleoprotein domain family member 7.
   
 
 0.947
HEXIM2
HEXIM P-TEFb complex subunit 2.
    
 
 0.940
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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