MMP16 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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[Homology]

Score

MMP16

Matrix metallopeptidase 16. (607 aa)

Predicted Functional Partners:

MMP13

0.906

HBEGF

0.899

TIMP2

0.832

TGFBR3

0.798

TIMP3

0.718

TIMP4

0.670

MMP14

0.659

FURIN

0.633

GNAI1

0.627

GNAI3

0.627

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FURIN	MMP14	ENSCAFP00000065874	ENSCAFP00000016472	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Matrix metallopeptidase 14.	0.812
FURIN	MMP16	ENSCAFP00000065874	ENSCAFP00000013128	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Matrix metallopeptidase 16.	0.633
FURIN	TIMP2	ENSCAFP00000065874	ENSCAFP00000035219	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.	0.509
FURIN	TIMP3	ENSCAFP00000065874	ENSCAFP00000040576	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	TIMP metallopeptidase inhibitor 3.	0.483
FURIN	TIMP4	ENSCAFP00000065874	ENSCAFP00000007442	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Metalloproteinase inhibitor 4.	0.542
GNAI1	MMP14	ENSCAFP00000024156	ENSCAFP00000016472	G protein subunit alpha i1.	Matrix metallopeptidase 14.	0.627
GNAI1	MMP16	ENSCAFP00000024156	ENSCAFP00000013128	G protein subunit alpha i1.	Matrix metallopeptidase 16.	0.627
GNAI3	MMP14	ENSCAFP00000029356	ENSCAFP00000016472	G protein subunit alpha i3.	Matrix metallopeptidase 14.	0.627
GNAI3	MMP16	ENSCAFP00000029356	ENSCAFP00000013128	G protein subunit alpha i3.	Matrix metallopeptidase 16.	0.627
HBEGF	MMP13	ENSCAFP00000051029	ENSCAFP00000022174	Heparin binding EGF like growth factor.	Matrix metallopeptidase 13.	0.480
HBEGF	MMP14	ENSCAFP00000051029	ENSCAFP00000016472	Heparin binding EGF like growth factor.	Matrix metallopeptidase 14.	0.905
HBEGF	MMP16	ENSCAFP00000051029	ENSCAFP00000013128	Heparin binding EGF like growth factor.	Matrix metallopeptidase 16.	0.899
MMP13	HBEGF	ENSCAFP00000022174	ENSCAFP00000051029	Matrix metallopeptidase 13.	Heparin binding EGF like growth factor.	0.480
MMP13	MMP14	ENSCAFP00000022174	ENSCAFP00000016472	Matrix metallopeptidase 13.	Matrix metallopeptidase 14.	0.910
MMP13	MMP16	ENSCAFP00000022174	ENSCAFP00000013128	Matrix metallopeptidase 13.	Matrix metallopeptidase 16.	0.906
MMP13	TIMP2	ENSCAFP00000022174	ENSCAFP00000035219	Matrix metallopeptidase 13.	Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.	0.837
MMP13	TIMP3	ENSCAFP00000022174	ENSCAFP00000040576	Matrix metallopeptidase 13.	TIMP metallopeptidase inhibitor 3.	0.815
MMP13	TIMP4	ENSCAFP00000022174	ENSCAFP00000007442	Matrix metallopeptidase 13.	Metalloproteinase inhibitor 4.	0.594
MMP14	FURIN	ENSCAFP00000016472	ENSCAFP00000065874	Matrix metallopeptidase 14.	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.812
MMP14	GNAI1	ENSCAFP00000016472	ENSCAFP00000024156	Matrix metallopeptidase 14.	G protein subunit alpha i1.	0.627