STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFXN5Sidoreflexin. (340 aa)    
Predicted Functional Partners:
PPP2R5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
      
 0.697
B3GAT2
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2; Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins; Belongs to the glycosyltransferase 43 family.
   
  
 0.682
CNPY3
Canopy FGF signaling regulator 3.
      
 0.680
UMPS
Uridine monophosphate synthetase.
   
  
 0.611
CDC5L
Cell division cycle 5 like.
      
 0.574
GPANK1
G-patch domain and ankyrin repeats 1.
      
 0.562
TIMM22
Translocase of inner mitochondrial membrane 22.
   
  
 0.523
NDUFV2
NADH dehydrogenase [ubiquinone] flavoprotein 2.
   
 
 0.520
AGK
Acylglycerol kinase.
   
 
 0.509
ASCC3
Activating signal cointegrator 1 complex subunit 3.
      
 0.508
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.