STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRSepiapterin reductase. (267 aa)    
Predicted Functional Partners:
PAH
Phenylalanine hydroxylase.
   
 
 0.994
PTS
6-pyruvoyltetrahydropterin synthase.
  
 
 0.991
QDPR
Quinoid dihydropteridine reductase.
   
 0.976
TH
Tyrosine 3-monooxygenase; Plays an important role in the physiology of adrenergic neurons.
   
 
 0.930
TPH2
Tryptophan hydroxylase 2.
   
 
 0.907
TPH1
Tryptophan hydroxylase 1.
   
 
 0.907
AKR1C3
Aldo_ket_red domain-containing protein.
   
 0.891
LOC610164
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.842
CBR3
Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.834
LOC609048
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
     
 0.816
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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