| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BIRC2 | BIRC3 | ENSCAFP00000022277 | ENSCAFP00000050122 | Baculoviral IAP repeat containing 2. | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | 0.866 |
| BIRC2 | IKBKG | ENSCAFP00000022277 | ENSCAFP00000028998 | Baculoviral IAP repeat containing 2. | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.890 |
| BIRC2 | NOD1 | ENSCAFP00000022277 | ENSCAFP00000004572 | Baculoviral IAP repeat containing 2. | Nucleotide binding oligomerization domain containing 1. | 0.619 |
| BIRC2 | RIPK2 | ENSCAFP00000022277 | ENSCAFP00000013170 | Baculoviral IAP repeat containing 2. | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. | 0.966 |
| BIRC2 | TAB1 | ENSCAFP00000022277 | ENSCAFP00000001917 | Baculoviral IAP repeat containing 2. | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. | 0.932 |
| BIRC2 | TAB2 | ENSCAFP00000022277 | ENSCAFP00000000532 | Baculoviral IAP repeat containing 2. | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.908 |
| BIRC2 | TRAF6 | ENSCAFP00000022277 | ENSCAFP00000010159 | Baculoviral IAP repeat containing 2. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.871 |
| BIRC2 | XIAP | ENSCAFP00000022277 | ENSCAFP00000034255 | Baculoviral IAP repeat containing 2. | Baculoviral IAP-repeat containing protein 4. | 0.966 |
| BIRC3 | BIRC2 | ENSCAFP00000050122 | ENSCAFP00000022277 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | Baculoviral IAP repeat containing 2. | 0.866 |
| BIRC3 | IKBKG | ENSCAFP00000050122 | ENSCAFP00000028998 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | 0.890 |
| BIRC3 | NOD1 | ENSCAFP00000050122 | ENSCAFP00000004572 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | Nucleotide binding oligomerization domain containing 1. | 0.630 |
| BIRC3 | RIPK2 | ENSCAFP00000050122 | ENSCAFP00000013170 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. | 0.966 |
| BIRC3 | TAB1 | ENSCAFP00000050122 | ENSCAFP00000001917 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. | 0.932 |
| BIRC3 | TAB2 | ENSCAFP00000050122 | ENSCAFP00000000532 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.908 |
| BIRC3 | TRAF6 | ENSCAFP00000050122 | ENSCAFP00000010159 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.871 |
| BIRC3 | XIAP | ENSCAFP00000050122 | ENSCAFP00000034255 | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | Baculoviral IAP-repeat containing protein 4. | 0.965 |
| IKBKG | BIRC2 | ENSCAFP00000028998 | ENSCAFP00000022277 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Baculoviral IAP repeat containing 2. | 0.890 |
| IKBKG | BIRC3 | ENSCAFP00000028998 | ENSCAFP00000050122 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Baculoviral IAP repeat-containing protein 3; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non- canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins [...] | 0.890 |
| IKBKG | NOD1 | ENSCAFP00000028998 | ENSCAFP00000004572 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Nucleotide binding oligomerization domain containing 1. | 0.624 |
| IKBKG | RIPK2 | ENSCAFP00000028998 | ENSCAFP00000013170 | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. | 0.963 |
