STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLIT1Slit guidance ligand 1. (1534 aa)    
Predicted Functional Partners:
ROBO2
Roundabout guidance receptor 2.
   
 0.971
ROBO1
Roundabout guidance receptor 1.
   
 0.965
ROBO4
Roundabout guidance receptor 4.
   
 0.961
ROBO3
Roundabout guidance receptor 3.
    
 
 0.890
NTN1
Netrin 1.
   
 0.717
SEMA3F
Semaphorin 3F; Belongs to the semaphorin family.
      
 0.668
SEMA4F
Ssemaphorin 4F; Belongs to the semaphorin family.
      
 0.654
PPP4R4
Protein phosphatase 4 regulatory subunit 4.
     
 0.621
SERPINA9
Serpin family A member 9; Belongs to the serpin family.
      
 0.609
SEMA6D
Semaphorin 6D; Belongs to the semaphorin family.
      
 0.606
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.