STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PFKMATP-dependent 6-phosphofructokinase, muscle type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (853 aa)    
Predicted Functional Partners:
HK2
Hexokinase 2.
   
 
 0.884
HK3
Hexokinase 3.
   
 
 0.881
TKTL1
Transketolase like 1.
  
 0.868
TKT
Transketolase.
  
 0.868
HK1
Hexokinase 1.
   
 
 0.867
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.
   
 0.860
HKDC1
Hexokinase domain containing 1.
   
 
 0.859
FBP2
Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family.
  
 
 0.858
ALDOC
Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.
  
 0.836
TIGAR
TP53 induced glycolysis regulatory phosphatase.
  
 0.834
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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