STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CMYA5Cardiomyopathy associated 5. (3821 aa)    
Predicted Functional Partners:
NRAP
Nebulin related anchoring protein.
   
 
 0.908
PASK
PAS domain containing serine/threonine kinase.
    
 0.850
TRDN
Triadin; Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact. Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.
   
 0.845
MYOM1
Myomesin 1.
   
 
 0.760
ACTN2
Actinin alpha 2.
   
 
 0.733
ALMS1
ALMS1 centrosome and basal body associated protein.
  
 
 0.702
MYOM2
Uncharacterized protein.
   
 
 0.700
XIRP2
Xin actin binding repeat containing 2.
   
 
 0.690
SMYD1
SET and MYND domain containing 1.
   
 
 0.644
MYPN
Myopalladin.
   
 
 0.642
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]