SENP1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SENP1

SUMO specific peptidase 1. (690 aa)

Predicted Functional Partners:

SUMO2

0.944

ENSCAFP00000049214

0.904

SUMO1

0.904

ENSCAFP00000066119

0.792

UBA2

0.740

NUP133

0.723

KPNB1

0.696

SENP6

0.695

NUP43

0.692

SENP7

0.686

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAFP00000049214	ENSCAFP00000066119	ENSCAFP00000049214	ENSCAFP00000066119	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.744
ENSCAFP00000049214	KPNB1	ENSCAFP00000049214	ENSCAFP00000044873	Ubiquitin-like domain-containing protein.	Karyopherin subunit beta 1.	0.536
ENSCAFP00000049214	SENP1	ENSCAFP00000049214	ENSCAFP00000013302	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 1.	0.904
ENSCAFP00000049214	SENP6	ENSCAFP00000049214	ENSCAFP00000003969	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 6.	0.687
ENSCAFP00000049214	SENP7	ENSCAFP00000049214	ENSCAFP00000037040	Ubiquitin-like domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.652
ENSCAFP00000049214	SUMO2	ENSCAFP00000049214	ENSCAFP00000007040	Ubiquitin-like domain-containing protein.	Small ubiquitin-related modifier.	0.744
ENSCAFP00000049214	UBA2	ENSCAFP00000049214	ENSCAFP00000010792	Ubiquitin-like domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.893
ENSCAFP00000066119	ENSCAFP00000049214	ENSCAFP00000066119	ENSCAFP00000049214	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.744
ENSCAFP00000066119	SENP1	ENSCAFP00000066119	ENSCAFP00000013302	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 1.	0.792
ENSCAFP00000066119	SENP6	ENSCAFP00000066119	ENSCAFP00000003969	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 6.	0.732
ENSCAFP00000066119	SENP7	ENSCAFP00000066119	ENSCAFP00000037040	Ubiquitin-like domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.755
ENSCAFP00000066119	SUMO1	ENSCAFP00000066119	ENSCAFP00000052182	Ubiquitin-like domain-containing protein.	Rad60-SLD domain-containing protein.	0.744
ENSCAFP00000066119	UBA2	ENSCAFP00000066119	ENSCAFP00000010792	Ubiquitin-like domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.822
KPNB1	ENSCAFP00000049214	ENSCAFP00000044873	ENSCAFP00000049214	Karyopherin subunit beta 1.	Ubiquitin-like domain-containing protein.	0.536
KPNB1	SENP1	ENSCAFP00000044873	ENSCAFP00000013302	Karyopherin subunit beta 1.	SUMO specific peptidase 1.	0.696
KPNB1	SUMO1	ENSCAFP00000044873	ENSCAFP00000052182	Karyopherin subunit beta 1.	Rad60-SLD domain-containing protein.	0.536
NUP133	NUP43	ENSCAFP00000017925	ENSCAFP00000000567	Nucleoporin 133.	Nucleoporin 43.	0.998
NUP133	SENP1	ENSCAFP00000017925	ENSCAFP00000013302	Nucleoporin 133.	SUMO specific peptidase 1.	0.723
NUP133	SENP6	ENSCAFP00000017925	ENSCAFP00000003969	Nucleoporin 133.	SUMO specific peptidase 6.	0.412
NUP133	SENP7	ENSCAFP00000017925	ENSCAFP00000037040	Nucleoporin 133.	ULP_PROTEASE domain-containing protein.	0.412