COL2A1 protein (Canis lupus familiaris) - STRING interaction network

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Score

COL2A1

Collagen type II alpha 1 chain. (1488 aa)

Predicted Functional Partners:

ACAN

0.944

CD44

0.931

COL1A1

0.925

COL11A2

0.893

ITGA6

0.889

ITGB8

0.889

GP6

0.882

ITGB1

0.881

COL11A1

0.879

MMP13

0.872

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAN	CD44	ENSCAFP00000065577	ENSCAFP00000050335	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	CD44 antigen.	0.643
ACAN	COL11A1	ENSCAFP00000065577	ENSCAFP00000053725	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Collagen type XI alpha 1 chain.	0.549
ACAN	COL1A1	ENSCAFP00000065577	ENSCAFP00000025056	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen).	0.753
ACAN	COL2A1	ENSCAFP00000065577	ENSCAFP00000013330	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Collagen type II alpha 1 chain.	0.944
ACAN	ITGB1	ENSCAFP00000065577	ENSCAFP00000005722	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Integrin beta; Belongs to the integrin beta chain family.	0.516
ACAN	MMP13	ENSCAFP00000065577	ENSCAFP00000022174	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	Matrix metallopeptidase 13.	0.933
CD44	ACAN	ENSCAFP00000050335	ENSCAFP00000065577	CD44 antigen.	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	0.643
CD44	COL1A1	ENSCAFP00000050335	ENSCAFP00000025056	CD44 antigen.	Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen).	0.934
CD44	COL2A1	ENSCAFP00000050335	ENSCAFP00000013330	CD44 antigen.	Collagen type II alpha 1 chain.	0.931
CD44	ITGA6	ENSCAFP00000050335	ENSCAFP00000054417	CD44 antigen.	Integrin subunit alpha 6; Belongs to the integrin alpha chain family.	0.546
CD44	ITGB1	ENSCAFP00000050335	ENSCAFP00000005722	CD44 antigen.	Integrin beta; Belongs to the integrin beta chain family.	0.749
CD44	MMP13	ENSCAFP00000050335	ENSCAFP00000022174	CD44 antigen.	Matrix metallopeptidase 13.	0.503
COL11A1	ACAN	ENSCAFP00000053725	ENSCAFP00000065577	Collagen type XI alpha 1 chain.	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	0.549
COL11A1	COL11A2	ENSCAFP00000053725	ENSCAFP00000001293	Collagen type XI alpha 1 chain.	Collagen type XI alpha 2 chain.	0.807
COL11A1	COL1A1	ENSCAFP00000053725	ENSCAFP00000025056	Collagen type XI alpha 1 chain.	Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen).	0.554
COL11A1	COL2A1	ENSCAFP00000053725	ENSCAFP00000013330	Collagen type XI alpha 1 chain.	Collagen type II alpha 1 chain.	0.879
COL11A1	MMP13	ENSCAFP00000053725	ENSCAFP00000022174	Collagen type XI alpha 1 chain.	Matrix metallopeptidase 13.	0.401
COL11A2	COL11A1	ENSCAFP00000001293	ENSCAFP00000053725	Collagen type XI alpha 2 chain.	Collagen type XI alpha 1 chain.	0.807
COL11A2	COL2A1	ENSCAFP00000001293	ENSCAFP00000013330	Collagen type XI alpha 2 chain.	Collagen type II alpha 1 chain.	0.893
COL1A1	ACAN	ENSCAFP00000025056	ENSCAFP00000065577	Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen).	Aggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage.	0.753