MYOD1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MYOD1

Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)

Predicted Functional Partners:

EP300

0.953

ID1

0.941

PAX7

0.933

FBXO32

0.912

TBP

0.898

TBPL2

0.894

TCF3

0.884

MEF2C

0.881

MEF2A

0.880

CREBBP

0.873

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	EP300	ENSCAFP00000036447	ENSCAFP00000001585	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	MEF2A	ENSCAFP00000036447	ENSCAFP00000046375	CREB binding protein.	Myocyte enhancer factor 2A.	0.554
CREBBP	MEF2C	ENSCAFP00000036447	ENSCAFP00000053374	CREB binding protein.	Myocyte enhancer factor 2C.	0.730
CREBBP	MYOD1	ENSCAFP00000036447	ENSCAFP00000013332	CREB binding protein.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.873
CREBBP	TBP	ENSCAFP00000036447	ENSCAFP00000065523	CREB binding protein.	TATA-box binding protein.	0.506
CREBBP	TCF3	ENSCAFP00000036447	ENSCAFP00000028831	CREB binding protein.	Transcription factor 3.	0.936
EP300	CREBBP	ENSCAFP00000001585	ENSCAFP00000036447	E1A binding protein p300.	CREB binding protein.	0.999
EP300	MEF2A	ENSCAFP00000001585	ENSCAFP00000046375	E1A binding protein p300.	Myocyte enhancer factor 2A.	0.858
EP300	MEF2C	ENSCAFP00000001585	ENSCAFP00000053374	E1A binding protein p300.	Myocyte enhancer factor 2C.	0.839
EP300	MYOD1	ENSCAFP00000001585	ENSCAFP00000013332	E1A binding protein p300.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.953
EP300	TCF3	ENSCAFP00000001585	ENSCAFP00000028831	E1A binding protein p300.	Transcription factor 3.	0.843
FBXO32	MYOD1	ENSCAFP00000034565	ENSCAFP00000013332	F-box protein 32.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.912
ID1	MYOD1	ENSCAFP00000010470	ENSCAFP00000013332	Inhibitor of DNA binding 1, HLH protein.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.941
ID1	TCF3	ENSCAFP00000010470	ENSCAFP00000028831	Inhibitor of DNA binding 1, HLH protein.	Transcription factor 3.	0.954
MEF2A	CREBBP	ENSCAFP00000046375	ENSCAFP00000036447	Myocyte enhancer factor 2A.	CREB binding protein.	0.554
MEF2A	EP300	ENSCAFP00000046375	ENSCAFP00000001585	Myocyte enhancer factor 2A.	E1A binding protein p300.	0.858
MEF2A	MEF2C	ENSCAFP00000046375	ENSCAFP00000053374	Myocyte enhancer factor 2A.	Myocyte enhancer factor 2C.	0.995
MEF2A	MYOD1	ENSCAFP00000046375	ENSCAFP00000013332	Myocyte enhancer factor 2A.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.880
MEF2A	PAX7	ENSCAFP00000046375	ENSCAFP00000022903	Myocyte enhancer factor 2A.	Paired box 7.	0.547
MEF2C	CREBBP	ENSCAFP00000053374	ENSCAFP00000036447	Myocyte enhancer factor 2C.	CREB binding protein.	0.730

page 1 of 3

Server load: low (20%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About