STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
COPS4COP9 signalosome subunit 4. (406 aa)    
Predicted Functional Partners:
COPS5
COP9 signalosome subunit 5.
   
 0.992
COPS3
COP9 signalosome subunit 3.
   
 0.992
COPS6
COP9 signalosome subunit 6.
   
 0.987
COPS2
COP9 signalosome subunit 2.
   
 0.987
COPS7A
COP9 signalosome subunit 7A.
   
 0.979
GPS1
G protein pathway suppressor 1.
   
 0.978
COPS7B
COP9 signalosome subunit 7B.
   
 0.976
CUL3
Cullin 3; Belongs to the cullin family.
    
 
 0.953
COPS8
PCI domain-containing protein.
   
 0.940
J9NSW9_CANLF
CSN8_PSD8_EIF3K domain-containing protein.
   
 0.939
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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