STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPHA6EPH receptor A6; Belongs to the protein kinase superfamily. Tyr protein kinase family. (320 aa)    
Predicted Functional Partners:
RASA1
RAS p21 protein activator 1.
   
 0.911
ABL1
Tyrosine-protein kinase.
   
0.909
NGEF
Neuronal guanine nucleotide exchange factor.
    
 0.908
F1PRX9_CANLF
Eph LBD domain-containing protein.
 
      0.898
EFNA3
Ephrin RBD domain-containing protein; Belongs to the ephrin family.
   
 0.801
EFNA1
Ephrin A1; Belongs to the ephrin family.
   
 0.797
ARL16
ADP ribosylation factor like GTPase 16.
    
 
 0.796
IRF2BP1
Interferon regulatory factor 2 binding protein 1.
      
 0.789
CARMIL1
Capping protein regulator and myosin 1 linker 1.
      
 0.739
EFNA5
Ephrin A5; Belongs to the ephrin family.
   
 
 0.664
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.