STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HPSEHeparanase. (545 aa)    
Predicted Functional Partners:
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
     
 0.959
HPSE2
Heparanase 2 (inactive).
  
  
0.904
IDS
Iduronate 2-sulfatase.
     
 0.901
TM6SF1
Transmembrane 6 superfamily member 1.
   
  
 0.648
BSDC1
BSD domain containing 1.
      
 0.647
VSTM2B
V-set and transmembrane domain containing 2B.
      
 0.637
PNPLA7
Patatin like phospholipase domain containing 7.
   
  
 0.576
SIAE
Sialic acid acetylesterase.
      
 0.573
DPP7
Dipeptidyl peptidase 7.
      
 0.560
DNASE2
Deoxyribonuclease 2, lysosomal.
      
 0.560
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.