STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (316 aa)    
Predicted Functional Partners:
SPAG5
Sperm associated antigen 5.
   
 
 0.921
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
  
 0.906
CDCA3
Cell division cycle associated 3.
   
  
 0.879
TACC3
Transforming acidic coiled-coil containing protein 3.
   
  
 0.860
NUF2
NUF2 component of NDC80 kinetochore complex.
   
  
 0.840
PRPF19
Pre-mRNA processing factor 19.
    
   0.811
CKAP2L
Cytoskeleton associated protein 2 like.
   
  
 0.805
RACGAP1
Rac GTPase activating protein 1.
   
  
 0.785
CCNA2
Cyclin A2; Belongs to the cyclin family.
   
  
 0.752
PLK1
Serine/threonine-protein kinase PLK.
   
  
 0.710
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.