LOC100686073 protein (Canis lupus familiaris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC100686073

Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family. (61 aa)

Predicted Functional Partners:

TESMIN

0.597

ATP7B

0.439

ATOX1

0.432

LOC611632

0.428

CP

0.428

CKS1B

0.425

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOX1	ATP7B	ENSCAFP00000026329	ENSCAFP00000006351	Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family.	ATPase copper transporting beta.	0.944
ATOX1	CP	ENSCAFP00000026329	ENSCAFP00000046239	Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.812
ATOX1	LOC100686073	ENSCAFP00000026329	ENSCAFP00000013400	Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family.	Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.432
ATOX1	LOC611632	ENSCAFP00000026329	ENSCAFP00000043372	Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family.	Uncharacterized protein; Belongs to the multicopper oxidase family.	0.812
ATP7B	ATOX1	ENSCAFP00000006351	ENSCAFP00000026329	ATPase copper transporting beta.	Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family.	0.944
ATP7B	CKS1B	ENSCAFP00000006351	ENSCAFP00000060934	ATPase copper transporting beta.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.453
ATP7B	CP	ENSCAFP00000006351	ENSCAFP00000046239	ATPase copper transporting beta.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.893
ATP7B	LOC100686073	ENSCAFP00000006351	ENSCAFP00000013400	ATPase copper transporting beta.	Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.439
ATP7B	LOC611632	ENSCAFP00000006351	ENSCAFP00000043372	ATPase copper transporting beta.	Uncharacterized protein; Belongs to the multicopper oxidase family.	0.893
CKS1B	ATP7B	ENSCAFP00000060934	ENSCAFP00000006351	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	ATPase copper transporting beta.	0.453
CKS1B	LOC100686073	ENSCAFP00000060934	ENSCAFP00000013400	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.425
CP	ATOX1	ENSCAFP00000046239	ENSCAFP00000026329	Ceruloplasmin; Belongs to the multicopper oxidase family.	Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family.	0.812
CP	ATP7B	ENSCAFP00000046239	ENSCAFP00000006351	Ceruloplasmin; Belongs to the multicopper oxidase family.	ATPase copper transporting beta.	0.893
CP	LOC100686073	ENSCAFP00000046239	ENSCAFP00000013400	Ceruloplasmin; Belongs to the multicopper oxidase family.	Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	0.428
CP	LOC611632	ENSCAFP00000046239	ENSCAFP00000043372	Ceruloplasmin; Belongs to the multicopper oxidase family.	Uncharacterized protein; Belongs to the multicopper oxidase family.	0.806
LOC100686073	ATOX1	ENSCAFP00000013400	ENSCAFP00000026329	Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family.	0.432
LOC100686073	ATP7B	ENSCAFP00000013400	ENSCAFP00000006351	Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	ATPase copper transporting beta.	0.439
LOC100686073	CKS1B	ENSCAFP00000013400	ENSCAFP00000060934	Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.425
LOC100686073	CP	ENSCAFP00000013400	ENSCAFP00000046239	Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Ceruloplasmin; Belongs to the multicopper oxidase family.	0.428
LOC100686073	LOC611632	ENSCAFP00000013400	ENSCAFP00000043372	Metallothionein-1; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids; Belongs to the metallothionein superfamily. Type 1 family.	Uncharacterized protein; Belongs to the multicopper oxidase family.	0.428

page 1 of 2

Server load: low (24%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About