STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LHX5LIM homeobox 5. (402 aa)    
Predicted Functional Partners:
DBX2
Developing brain homeobox 2.
    
 
 0.820
CCNK
Cyclin K; Belongs to the cyclin family.
    
   0.720
OLIG3
Oligodendrocyte transcription factor 3.
   
 
 0.708
ZIC4
Zic family member 4.
   
 0.654
DBX1
Developing brain homeobox 1.
   
 
 0.649
LDB1
LIM domain binding 1.
    
 
 0.647
BARHL1
BarH like homeobox 1.
   
 
 0.624
LDB2
LIM domain binding 2.
    
 
 0.614
NEUROD2
Neurogenic differentiation factor.
   
 
 0.600
RELN
Reelin.
      
 0.564
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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