STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IVDIsovaleryl-CoA dehydrogenase. (426 aa)    
Predicted Functional Partners:
MCCC2
Methylcrotonoyl-CoA carboxylase 2.
 
 
 0.990
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
  
 0.976
DBT
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.972
ECHS1
Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.962
HADHA
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.954
EHHADH
Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.954
ACADM
Acyl-CoA dehydrogenase medium chain.
  
0.938
LOC477365
Epimerase domain-containing protein.
   
 
 0.902
ETFB
Electron transfer flavoprotein subunit beta.
 
 0.900
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.899
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.