STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNF408Zinc finger protein 408. (752 aa)    
Predicted Functional Partners:
GPATCH3
G-patch domain containing 3.
   
    0.967
TSPAN12
Tetraspanin.
      
 0.889
RCBTB1
RCC1 and BTB domain containing protein 1.
    
 0.796
CCNJ
Cyclin J; Belongs to the cyclin family.
   
 
 0.760
FZD4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 
 0.742
KIF11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 
 0.738
NDP
Norrin cystine knot growth factor NDP.
    
 
 0.721
GAPDHS
Glyceraldehyde-3-phosphate dehydrogenase.
   
 
 0.696
ARHGAP31
Rho GTPase activating protein 31.
      
 0.692
ACOT13
Acyl-CoA thioesterase 13.
      
 0.688
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.