| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DFFB | NKX2-2 | ENSCAFP00000058291 | ENSCAFP00000063267 | DNA fragmentation factor subunit beta. | Thyroid transcription factor 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis; Belongs to the NK-2 homeobox family. | 0.425 |
| DFFB | NKX6-1 | ENSCAFP00000058291 | ENSCAFP00000013462 | DNA fragmentation factor subunit beta. | NK6 homeobox 1. | 0.591 |
| FAM92B | NKX6-1 | ENSCAFP00000053398 | ENSCAFP00000013462 | Family with sequence similarity 92 member B. | NK6 homeobox 1. | 0.541 |
| FOXA2 | GCG | ENSCAFP00000007716 | ENSCAFP00000015307 | Forkhead box A2. | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | 0.519 |
| FOXA2 | INS | ENSCAFP00000007716 | ENSCAFP00000051648 | Forkhead box A2. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.623 |
| FOXA2 | NKX2-2 | ENSCAFP00000007716 | ENSCAFP00000063267 | Forkhead box A2. | Thyroid transcription factor 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis; Belongs to the NK-2 homeobox family. | 0.560 |
| FOXA2 | NKX6-1 | ENSCAFP00000007716 | ENSCAFP00000013462 | Forkhead box A2. | NK6 homeobox 1. | 0.580 |
| FOXA2 | PDX1 | ENSCAFP00000007716 | ENSCAFP00000010069 | Forkhead box A2. | Pancreatic and duodenum homeobox 1. | 0.634 |
| GCG | FOXA2 | ENSCAFP00000015307 | ENSCAFP00000007716 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | Forkhead box A2. | 0.519 |
| GCG | INS | ENSCAFP00000015307 | ENSCAFP00000051648 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.932 |
| GCG | NEUROG3 | ENSCAFP00000015307 | ENSCAFP00000031746 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | Neurogenin 3. | 0.564 |
| GCG | NKX6-1 | ENSCAFP00000015307 | ENSCAFP00000013462 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | NK6 homeobox 1. | 0.576 |
| GCG | PDX1 | ENSCAFP00000015307 | ENSCAFP00000010069 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | Pancreatic and duodenum homeobox 1. | 0.720 |
| GCG | UCN3 | ENSCAFP00000015307 | ENSCAFP00000007854 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | Urocortin 3. | 0.571 |
| INS | FOXA2 | ENSCAFP00000051648 | ENSCAFP00000007716 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Forkhead box A2. | 0.623 |
| INS | GCG | ENSCAFP00000051648 | ENSCAFP00000015307 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia (By similarity). GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a [...] | 0.932 |
| INS | NEUROG3 | ENSCAFP00000051648 | ENSCAFP00000031746 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Neurogenin 3. | 0.610 |
| INS | NKX2-2 | ENSCAFP00000051648 | ENSCAFP00000063267 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Thyroid transcription factor 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis; Belongs to the NK-2 homeobox family. | 0.416 |
| INS | NKX6-1 | ENSCAFP00000051648 | ENSCAFP00000013462 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | NK6 homeobox 1. | 0.622 |
| INS | PDX1 | ENSCAFP00000051648 | ENSCAFP00000010069 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Pancreatic and duodenum homeobox 1. | 0.873 |
