ARHGAP1 protein (Canis lupus familiaris) - STRING interaction network

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Score

ARHGAP1

Cdc42 GTPase-activating protein. (439 aa)

Predicted Functional Partners:

CDC42-2

0.881

BNIP2

0.844

CDC42

0.810

J9NYK5_CANLF

0.810

J9P730_CANLF

0.810

RHOC

0.789

PRR5

0.692

RANBP1

0.689

CORO1A

0.688

RAC1

0.671

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP1	BNIP2	ENSCAFP00000013467	ENSCAFP00000051399	Cdc42 GTPase-activating protein.	BCL2 interacting protein 2.	0.844
ARHGAP1	CDC42	ENSCAFP00000013467	ENSCAFP00000021684	Cdc42 GTPase-activating protein.	Cell division cycle 42.	0.810
ARHGAP1	CDC42-2	ENSCAFP00000013467	ENSCAFP00000060180	Cdc42 GTPase-activating protein.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.881
ARHGAP1	CORO1A	ENSCAFP00000013467	ENSCAFP00000053109	Cdc42 GTPase-activating protein.	Coronin; Belongs to the WD repeat coronin family.	0.688
ARHGAP1	J9NYK5_CANLF	ENSCAFP00000013467	ENSCAFP00000038374	Cdc42 GTPase-activating protein.	Uncharacterized protein.	0.810
ARHGAP1	J9P730_CANLF	ENSCAFP00000013467	ENSCAFP00000041464	Cdc42 GTPase-activating protein.	Uncharacterized protein.	0.810
ARHGAP1	PRR5	ENSCAFP00000013467	ENSCAFP00000041948	Cdc42 GTPase-activating protein.	Proline rich 5.	0.692
ARHGAP1	RAC1	ENSCAFP00000013467	ENSCAFP00000032062	Cdc42 GTPase-activating protein.	Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...]	0.671
ARHGAP1	RANBP1	ENSCAFP00000013467	ENSCAFP00000040218	Cdc42 GTPase-activating protein.	RAN binding protein 1.	0.689
ARHGAP1	RHOC	ENSCAFP00000013467	ENSCAFP00000059310	Cdc42 GTPase-activating protein.	Uncharacterized protein.	0.789
BNIP2	ARHGAP1	ENSCAFP00000051399	ENSCAFP00000013467	BCL2 interacting protein 2.	Cdc42 GTPase-activating protein.	0.844
BNIP2	CDC42	ENSCAFP00000051399	ENSCAFP00000021684	BCL2 interacting protein 2.	Cell division cycle 42.	0.601
BNIP2	CDC42-2	ENSCAFP00000051399	ENSCAFP00000060180	BCL2 interacting protein 2.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.792
BNIP2	J9NYK5_CANLF	ENSCAFP00000051399	ENSCAFP00000038374	BCL2 interacting protein 2.	Uncharacterized protein.	0.601
BNIP2	J9P730_CANLF	ENSCAFP00000051399	ENSCAFP00000041464	BCL2 interacting protein 2.	Uncharacterized protein.	0.601
BNIP2	PRR5	ENSCAFP00000051399	ENSCAFP00000041948	BCL2 interacting protein 2.	Proline rich 5.	0.419
CDC42	ARHGAP1	ENSCAFP00000021684	ENSCAFP00000013467	Cell division cycle 42.	Cdc42 GTPase-activating protein.	0.810
CDC42	BNIP2	ENSCAFP00000021684	ENSCAFP00000051399	Cell division cycle 42.	BCL2 interacting protein 2.	0.601
CDC42	CDC42-2	ENSCAFP00000021684	ENSCAFP00000060180	Cell division cycle 42.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...]	0.801
CDC42	J9P730_CANLF	ENSCAFP00000021684	ENSCAFP00000041464	Cell division cycle 42.	Uncharacterized protein.	0.801