Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ARSBArylsulfatase B. (535 aa)    
Predicted Functional Partners:
IDUA
Alpha-L-iduronidase.
   
 0.950
ARSG
Arylsulfatase G; Displays arylsulfatase activity with pseudosubstrates at acidic pH, such as p-nitrocatechol sulfate.
  
0.933
SUMF1
Sulfatase modifying factor 1.
  
 
 0.911
ARSA
Arylsulfatase A.
  
0.898
ARSK
Arylsulfatase K.
  
 
 0.886
SPAM1
Hyaluronidase.
     
 0.850
LOC609321
Hyaluronidase.
     
 0.850
HYAL3
Hyaluronidase.
     
 0.850
HYAL2
Hyaluronidase.
     
 0.843
FARSB
Phenylalanyl-tRNA synthetase subunit beta.
    
 
 0.824
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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