STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHTF1Putative homeodomain transcription factor 1. (762 aa)    
Predicted Functional Partners:
RSBN1
Round spermatid basic protein 1.
 
    
 0.933
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
   
 
 0.831
NAGK
BcrAD_BadFG domain-containing protein.
   
  
 0.809
BCL2L15
BCL2 like 15.
      
 0.801
ZRANB3
Zinc finger RANBP2-type containing 3.
    
 
 0.669
RAB3GAP1
RAB3 GTPase activating protein catalytic subunit 1.
   
  
 0.649
ESYT2
Extended synaptotagmin 2.
    
 
 0.620
PTPRN2
Protein tyrosine phosphatase receptor type N2.
    
 
 0.596
USP16
Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
   
  
 0.589
RWDD2B
RWD domain-containing protein.
   
  
 0.576
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.