TRIO protein (Canis lupus familiaris) - STRING interaction network

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Score

TRIO

Trio Rho guanine nucleotide exchange factor. (3053 aa)

Predicted Functional Partners:

CACUL1

0.783

NUDCD1

0.663

NOX3

0.648

TMEM181

0.632

RHOBTB1

0.616

RHOBTB2

0.616

ARID1B

0.613

RAC2

0.561

RAC3

0.561

RAC1

0.561

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID1B	TMEM181	ENSCAFP00000058134	ENSCAFP00000000925	AT-rich interaction domain 1B.	Transmembrane protein 181.	0.533
ARID1B	TRIO	ENSCAFP00000058134	ENSCAFP00000013586	AT-rich interaction domain 1B.	Trio Rho guanine nucleotide exchange factor.	0.613
CACUL1	TMEM181	ENSCAFP00000017676	ENSCAFP00000000925	CDK2 associated cullin domain 1; Belongs to the cullin family.	Transmembrane protein 181.	0.694
CACUL1	TRIO	ENSCAFP00000017676	ENSCAFP00000013586	CDK2 associated cullin domain 1; Belongs to the cullin family.	Trio Rho guanine nucleotide exchange factor.	0.783
NOX3	RAC1	ENSCAFP00000000844	ENSCAFP00000032062	Predicted NADPH oxidase-3.	Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...]	0.813
NOX3	RAC2	ENSCAFP00000000844	ENSCAFP00000002174	Predicted NADPH oxidase-3.	Rac family small GTPase 2.	0.770
NOX3	RAC3	ENSCAFP00000000844	ENSCAFP00000008868	Predicted NADPH oxidase-3.	Uncharacterized protein.	0.539
NOX3	TMEM181	ENSCAFP00000000844	ENSCAFP00000000925	Predicted NADPH oxidase-3.	Transmembrane protein 181.	0.539
NOX3	TRIO	ENSCAFP00000000844	ENSCAFP00000013586	Predicted NADPH oxidase-3.	Trio Rho guanine nucleotide exchange factor.	0.648
NUDCD1	TRIO	ENSCAFP00000001029	ENSCAFP00000013586	NudC domain containing 1.	Trio Rho guanine nucleotide exchange factor.	0.663
RAC1	NOX3	ENSCAFP00000032062	ENSCAFP00000000844	Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...]	Predicted NADPH oxidase-3.	0.813
RAC1	RAC2	ENSCAFP00000032062	ENSCAFP00000002174	Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...]	Rac family small GTPase 2.	0.954
RAC1	TRIO	ENSCAFP00000032062	ENSCAFP00000013586	Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...]	Trio Rho guanine nucleotide exchange factor.	0.561
RAC2	NOX3	ENSCAFP00000002174	ENSCAFP00000000844	Rac family small GTPase 2.	Predicted NADPH oxidase-3.	0.770
RAC2	RAC1	ENSCAFP00000002174	ENSCAFP00000032062	Rac family small GTPase 2.	Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...]	0.954
RAC2	RAC3	ENSCAFP00000002174	ENSCAFP00000008868	Rac family small GTPase 2.	Uncharacterized protein.	0.765
RAC2	TRIO	ENSCAFP00000002174	ENSCAFP00000013586	Rac family small GTPase 2.	Trio Rho guanine nucleotide exchange factor.	0.561
RAC3	NOX3	ENSCAFP00000008868	ENSCAFP00000000844	Uncharacterized protein.	Predicted NADPH oxidase-3.	0.539
RAC3	RAC2	ENSCAFP00000008868	ENSCAFP00000002174	Uncharacterized protein.	Rac family small GTPase 2.	0.765
RAC3	TRIO	ENSCAFP00000008868	ENSCAFP00000013586	Uncharacterized protein.	Trio Rho guanine nucleotide exchange factor.	0.561