STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WRNIP1Werner helicase interacting protein 1. (445 aa)    
Predicted Functional Partners:
WRN
WRN RecQ like helicase.
  
 
 0.862
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 
 0.749
BLM
BLM RecQ like helicase.
  
 
 0.646
POLD2
DNA polymerase delta 2, accessory subunit.
    
 
 0.598
RECQL5
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 
 0.570
RECQL
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
  
 0.563
HSCB
HscB mitochondrial iron-sulfur cluster cochaperone.
  
  
 0.540
DNA2
DNA replication helicase/nuclease 2.
    
 
 0.538
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 
 0.519
ZNF576
Zinc finger protein 576.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.