STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE8BPhosphodiesterase 8B; Belongs to the cyclic nucleotide phosphodiesterase family. (350 aa)    
Predicted Functional Partners:
ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.790
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
     
 0.790
AMPD3
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
     
 0.790
AMPD2
Adenosine monophosphate deaminase 2.
     
 0.786
ADK
Adenosine kinase.
     
 0.783
APRT
Adenine phosphoribosyltransferase.
     
 0.777
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
     
 0.775
AMPD1
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
     
 0.774
AK8
Adenylate kinase 8; Belongs to the adenylate kinase family.
     
 0.771
NT5C
5', 3'-nucleotidase, cytosolic.
     
 0.771
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]