CRHBP protein (Canis lupus familiaris) - STRING interaction network

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CRHBP

Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)

Predicted Functional Partners:

CRH

0.991

LOC610380

0.891

UCN

0.844

CRHR2

0.835

MAPK15

0.731

GPATCH1

0.637

UCN3

0.599

AGGF1

0.599

NUCB2

0.587

CLIP1

0.569

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGGF1	CLIP1	ENSCAFP00000054296	ENSCAFP00000065838	Angiogenic factor with G-patch and FHA domains 1.	CAP-Gly domain containing linker protein 1.	0.742
AGGF1	CRHBP	ENSCAFP00000054296	ENSCAFP00000013633	Angiogenic factor with G-patch and FHA domains 1.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.599
CLIP1	AGGF1	ENSCAFP00000065838	ENSCAFP00000054296	CAP-Gly domain containing linker protein 1.	Angiogenic factor with G-patch and FHA domains 1.	0.742
CLIP1	CRHBP	ENSCAFP00000065838	ENSCAFP00000013633	CAP-Gly domain containing linker protein 1.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.569
CRH	CRHBP	ENSCAFP00000040748	ENSCAFP00000013633	Corticoliberin; Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.991
CRH	CRHR2	ENSCAFP00000040748	ENSCAFP00000004610	Corticoliberin; Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	0.996
CRH	LOC610380	ENSCAFP00000040748	ENSCAFP00000020012	Corticoliberin; Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.998
CRH	UCN	ENSCAFP00000040748	ENSCAFP00000031248	Corticoliberin; Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.	Urocortin.	0.983
CRH	UCN3	ENSCAFP00000040748	ENSCAFP00000007854	Corticoliberin; Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.	Urocortin 3.	0.957
CRHBP	AGGF1	ENSCAFP00000013633	ENSCAFP00000054296	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Angiogenic factor with G-patch and FHA domains 1.	0.599
CRHBP	CLIP1	ENSCAFP00000013633	ENSCAFP00000065838	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	CAP-Gly domain containing linker protein 1.	0.569
CRHBP	CRH	ENSCAFP00000013633	ENSCAFP00000040748	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Corticoliberin; Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.	0.991
CRHBP	CRHR2	ENSCAFP00000013633	ENSCAFP00000004610	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	0.835
CRHBP	GPATCH1	ENSCAFP00000013633	ENSCAFP00000050247	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	G-patch domain containing 1.	0.637
CRHBP	LOC610380	ENSCAFP00000013633	ENSCAFP00000020012	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.891
CRHBP	MAPK15	ENSCAFP00000013633	ENSCAFP00000044900	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Mitogen-activated protein kinase.	0.731
CRHBP	NUCB2	ENSCAFP00000013633	ENSCAFP00000034200	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Nucleobindin 2.	0.587
CRHBP	UCN	ENSCAFP00000013633	ENSCAFP00000031248	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urocortin.	0.844
CRHBP	UCN3	ENSCAFP00000013633	ENSCAFP00000007854	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urocortin 3.	0.599
CRHR2	CRH	ENSCAFP00000004610	ENSCAFP00000040748	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	Corticoliberin; Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.	0.996

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