NIT2 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NIT2

Nitrilase family member 2. (283 aa)

Predicted Functional Partners:

DDO

0.917

GOT1L1

0.909

GOT1

0.902

RPL31

0.897

ENSCAFP00000041626

0.897

MDH1

0.895

PC

0.894

IDH3G

0.891

E2R735_CANLF

0.890

IL4I1

0.890

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDO	E2R735_CANLF	ENSCAFP00000005787	ENSCAFP00000003629	D-aspartate oxidase.	Amino_oxidase domain-containing protein.	0.891
DDO	GOT1	ENSCAFP00000005787	ENSCAFP00000013922	D-aspartate oxidase.	Aspartate aminotransferase.	0.911
DDO	GOT1L1	ENSCAFP00000005787	ENSCAFP00000009252	D-aspartate oxidase.	Glutamic-oxaloacetic transaminase 1 like 1.	0.926
DDO	IDH3G	ENSCAFP00000005787	ENSCAFP00000028461	D-aspartate oxidase.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.820
DDO	IL4I1	ENSCAFP00000005787	ENSCAFP00000005131	D-aspartate oxidase.	Interleukin 4 induced 1.	0.891
DDO	MDH1	ENSCAFP00000005787	ENSCAFP00000031562	D-aspartate oxidase.	Malate dehydrogenase.	0.893
DDO	NIT2	ENSCAFP00000005787	ENSCAFP00000013662	D-aspartate oxidase.	Nitrilase family member 2.	0.917
DDO	PC	ENSCAFP00000005787	ENSCAFP00000063198	D-aspartate oxidase.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.893
E2R735_CANLF	DDO	ENSCAFP00000003629	ENSCAFP00000005787	Amino_oxidase domain-containing protein.	D-aspartate oxidase.	0.891
E2R735_CANLF	GOT1	ENSCAFP00000003629	ENSCAFP00000013922	Amino_oxidase domain-containing protein.	Aspartate aminotransferase.	0.885
E2R735_CANLF	GOT1L1	ENSCAFP00000003629	ENSCAFP00000009252	Amino_oxidase domain-containing protein.	Glutamic-oxaloacetic transaminase 1 like 1.	0.881
E2R735_CANLF	IDH3G	ENSCAFP00000003629	ENSCAFP00000028461	Amino_oxidase domain-containing protein.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.881
E2R735_CANLF	IL4I1	ENSCAFP00000003629	ENSCAFP00000005131	Amino_oxidase domain-containing protein.	Interleukin 4 induced 1.	0.881
E2R735_CANLF	MDH1	ENSCAFP00000003629	ENSCAFP00000031562	Amino_oxidase domain-containing protein.	Malate dehydrogenase.	0.881
E2R735_CANLF	NIT2	ENSCAFP00000003629	ENSCAFP00000013662	Amino_oxidase domain-containing protein.	Nitrilase family member 2.	0.890
E2R735_CANLF	PC	ENSCAFP00000003629	ENSCAFP00000063198	Amino_oxidase domain-containing protein.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.886
ENSCAFP00000041626	NIT2	ENSCAFP00000041626	ENSCAFP00000013662	annotation not available	Nitrilase family member 2.	0.897
ENSCAFP00000041626	RPL31	ENSCAFP00000041626	ENSCAFP00000038384	annotation not available	Uncharacterized protein.	0.801
GOT1	DDO	ENSCAFP00000013922	ENSCAFP00000005787	Aspartate aminotransferase.	D-aspartate oxidase.	0.911
GOT1	E2R735_CANLF	ENSCAFP00000013922	ENSCAFP00000003629	Aspartate aminotransferase.	Amino_oxidase domain-containing protein.	0.885