STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESRP1Epithelial splicing regulatory protein 1. (623 aa)    
Predicted Functional Partners:
ENAH
ENAH actin regulator.
      
 0.678
ARHGEF11
Rho guanine nucleotide exchange factor 11.
      
 0.676
OSBPL3
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.672
GRHL2
Grainyhead like transcription factor 2.
   
  
 0.644
GRHL1
Grainyhead like transcription factor 1.
   
  
 0.644
ARHGEF10L
Rho guanine nucleotide exchange factor 10 like.
      
 0.637
ZEB1
Zinc finger E-box binding homeobox 1.
      
 0.613
SCRIB
Scribble planar cell polarity protein.
   
  
 0.573
RAB25
Ras-related protein Rab-25; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
   
  
 0.569
RBFOX2
RNA binding fox-1 homolog 2.
      
 0.552
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.