STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSG101Tumor susceptibility 101. (391 aa)    
Predicted Functional Partners:
VPS28
VPS28 subunit of ESCRT-I; Belongs to the VPS28 family.
   
 0.993
VPS37A
VPS37A subunit of ESCRT-I.
   
 0.988
VPS37B
VPS37B subunit of ESCRT-I.
   
 0.988
VPS37C
VPS37C subunit of ESCRT-I.
   
 0.987
HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate.
    
 0.983
VPS37D
VPS37D subunit of ESCRT-I.
   
 0.978
UBAP1
Uncharacterized protein.
   
 0.977
ENSCAFP00000048438
UMA domain-containing protein.
   
 0.977
CD63
Tetraspanin.
   
 
 0.956
VPS36
Vacuolar protein sorting 36 homolog.
    
 0.956
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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