PHF21A protein (Canis lupus familiaris) - STRING interaction network

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Score

PHF21A

PHD finger protein 21A. (680 aa)

Predicted Functional Partners:

HMG20B

0.966

RCOR1

0.956

KDM1A

0.955

HDAC1

0.874

ZNF217

0.842

HDAC2

0.804

HMG20A

0.747

MTA3

0.698

MTA2

0.698

MTA1

0.698

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HDAC1	HDAC2	ENSCAFP00000036819	ENSCAFP00000042408	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.958
HDAC1	HMG20A	ENSCAFP00000036819	ENSCAFP00000026696	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	High mobility group 20A.	0.531
HDAC1	HMG20B	ENSCAFP00000036819	ENSCAFP00000028341	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	High mobility group 20B.	0.791
HDAC1	KDM1A	ENSCAFP00000036819	ENSCAFP00000053375	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.893
HDAC1	MTA1	ENSCAFP00000036819	ENSCAFP00000027224	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Metastasis associated 1.	0.913
HDAC1	MTA2	ENSCAFP00000036819	ENSCAFP00000023249	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Metastasis associated 1 family member 2.	0.909
HDAC1	MTA3	ENSCAFP00000036819	ENSCAFP00000009773	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Metastasis associated 1 family member 3.	0.852
HDAC1	PHF21A	ENSCAFP00000036819	ENSCAFP00000013745	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	PHD finger protein 21A.	0.874
HDAC1	RCOR1	ENSCAFP00000036819	ENSCAFP00000026701	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 1.	0.941
HDAC1	ZNF217	ENSCAFP00000036819	ENSCAFP00000040038	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Zinc finger protein 217.	0.713
HDAC2	HDAC1	ENSCAFP00000042408	ENSCAFP00000036819	Histone deacetylase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.958
HDAC2	HMG20A	ENSCAFP00000042408	ENSCAFP00000026696	Histone deacetylase 2.	High mobility group 20A.	0.531
HDAC2	HMG20B	ENSCAFP00000042408	ENSCAFP00000028341	Histone deacetylase 2.	High mobility group 20B.	0.687
HDAC2	KDM1A	ENSCAFP00000042408	ENSCAFP00000053375	Histone deacetylase 2.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.915
HDAC2	MTA1	ENSCAFP00000042408	ENSCAFP00000027224	Histone deacetylase 2.	Metastasis associated 1.	0.913
HDAC2	MTA2	ENSCAFP00000042408	ENSCAFP00000023249	Histone deacetylase 2.	Metastasis associated 1 family member 2.	0.909
HDAC2	MTA3	ENSCAFP00000042408	ENSCAFP00000009773	Histone deacetylase 2.	Metastasis associated 1 family member 3.	0.852
HDAC2	PHF21A	ENSCAFP00000042408	ENSCAFP00000013745	Histone deacetylase 2.	PHD finger protein 21A.	0.804
HDAC2	RCOR1	ENSCAFP00000042408	ENSCAFP00000026701	Histone deacetylase 2.	REST corepressor 1.	0.942
HDAC2	ZNF217	ENSCAFP00000042408	ENSCAFP00000040038	Histone deacetylase 2.	Zinc finger protein 217.	0.491