STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PYROXD2Pyridine nucleotide-disulphide oxidoreductase domain 2. (580 aa)    
Predicted Functional Partners:
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.820
SIPA1L3
Signal induced proliferation associated 1 like 3.
      
 0.810
WDR97
WD_REPEATS_REGION domain-containing protein.
  
 
 0.730
NDUFAF6
NADH:ubiquinone oxidoreductase complex assembly factor 6.
  
 
 0.730
PLAAT1
Phospholipase A and acyltransferase 1.
     
 0.672
TPD52L2
TPD52 like 2.
      
 0.645
CDHR2
Cadherin related family member 2.
   
  
 0.619
ACCS
1-aminocyclopropane-1-carboxylate synthase homolog (inactive).
   
  
 0.618
YME1L1
YME1 like 1 ATPase.
      
 0.618
GASK1B
Golgi associated kinase 1B.
      
 0.617
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.