STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKP4Plakophilin 4. (1222 aa)    
Predicted Functional Partners:
JUP
Uncharacterized protein.
   
 0.814
PPFIA4
PTPRF interacting protein alpha 4.
   
  
 0.789
ZBTB33
Zinc finger and BTB domain containing 33.
    
 
 0.763
ERBIN
Erbb2 interacting protein.
   
 
 0.706
CUTA
CutA divalent cation tolerance homolog.
   
  
 0.699
PCDHA13
Protocadherin alpha 13.
    
 
 0.692
TMEM184B
Transmembrane protein 184B.
   
  
 0.686
DOK4
Docking protein 4.
      
 0.674
ADAMTSL5
ADAMTS like 5.
      
 0.646
ABI3BP
ABI family member 3 binding protein.
   
  
 0.635
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.