STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SORBS3Sorbin and SH3 domain containing 3. (306 aa)    
Predicted Functional Partners:
ENSCAFP00000065061
SoHo domain-containing protein.
 
      0.895
VCL
Vinculin.
   
 0.887
SPTBN4-2
Uncharacterized protein.
      
 0.696
DLG5
Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.
    
 
 0.692
FLOT1
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
 0.691
FLOT2
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
 0.683
TBXA2R
Thromboxane A2 receptor.
   
  
 0.667
PRDM10
PR/SET domain 10.
    
 
 0.661
AFDN
Afadin, adherens junction formation factor.
    
 0.658
LNX1
Ligand of numb-protein X 1.
   
 
 0.621
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.