| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFF3 | MAD2L2 | ENSCAFP00000052865 | ENSCAFP00000024383 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | Mitotic arrest deficient 2 like 2. | 0.991 |
| AFF3 | PCNA | ENSCAFP00000052865 | ENSCAFP00000009045 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.952 |
| AFF3 | POLH | ENSCAFP00000052865 | ENSCAFP00000002810 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | DNA polymerase eta. | 0.983 |
| AFF3 | POLI | ENSCAFP00000052865 | ENSCAFP00000000218 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | DNA polymerase iota. | 0.955 |
| AFF3 | POLK | ENSCAFP00000052865 | ENSCAFP00000013822 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | DNA polymerase kappa. | 0.975 |
| AFF3 | RAD51 | ENSCAFP00000052865 | ENSCAFP00000058998 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | DNA repair protein RAD51 homolog 1; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Part of a PALB2-scaffolded HR [...] | 0.916 |
| AFF3 | RAD51B | ENSCAFP00000052865 | ENSCAFP00000056881 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | RAD51 paralog B. | 0.790 |
| AFF3 | REV3L | ENSCAFP00000052865 | ENSCAFP00000051058 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | REV3 like, DNA directed polymerase zeta catalytic subunit. | 0.978 |
| AFF3 | TP53 | ENSCAFP00000052865 | ENSCAFP00000064590 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.443 |
| AFF3 | XPA | ENSCAFP00000052865 | ENSCAFP00000003578 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | XPA, DNA damage recognition and repair factor. | 0.718 |
| MAD2L2 | AFF3 | ENSCAFP00000024383 | ENSCAFP00000052865 | Mitotic arrest deficient 2 like 2. | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | 0.991 |
| MAD2L2 | PCNA | ENSCAFP00000024383 | ENSCAFP00000009045 | Mitotic arrest deficient 2 like 2. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.771 |
| MAD2L2 | POLH | ENSCAFP00000024383 | ENSCAFP00000002810 | Mitotic arrest deficient 2 like 2. | DNA polymerase eta. | 0.829 |
| MAD2L2 | POLI | ENSCAFP00000024383 | ENSCAFP00000000218 | Mitotic arrest deficient 2 like 2. | DNA polymerase iota. | 0.857 |
| MAD2L2 | POLK | ENSCAFP00000024383 | ENSCAFP00000013822 | Mitotic arrest deficient 2 like 2. | DNA polymerase kappa. | 0.804 |
| MAD2L2 | RAD51 | ENSCAFP00000024383 | ENSCAFP00000058998 | Mitotic arrest deficient 2 like 2. | DNA repair protein RAD51 homolog 1; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Part of a PALB2-scaffolded HR [...] | 0.914 |
| MAD2L2 | RAD51B | ENSCAFP00000024383 | ENSCAFP00000056881 | Mitotic arrest deficient 2 like 2. | RAD51 paralog B. | 0.710 |
| MAD2L2 | REV3L | ENSCAFP00000024383 | ENSCAFP00000051058 | Mitotic arrest deficient 2 like 2. | REV3 like, DNA directed polymerase zeta catalytic subunit. | 0.999 |
| PCNA | AFF3 | ENSCAFP00000009045 | ENSCAFP00000052865 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. | 0.952 |
| PCNA | MAD2L2 | ENSCAFP00000009045 | ENSCAFP00000024383 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Mitotic arrest deficient 2 like 2. | 0.771 |
