STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)    
Predicted Functional Partners:
SNCA
Alpha-synuclein; Belongs to the synuclein family.
    
 
 0.816
DRD2
D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.
   
 0.756
NFATC2
Nuclear factor of activated T cells 2.
      
 0.748
LPCAT1
Lysophosphatidylcholine acyltransferase 1.
    
 
 0.742
DRD3
Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.
   
 0.737
HOXA5
Homeobox A5.
      
 0.706
CAMK2G
Calcium/calmodulin dependent protein kinase II gamma.
     
  0.695
SLC18A2
Solute carrier family 18 member A2.
   
 
 0.681
PALM3
Paralemmin 3.
   
  
 0.587
SLC1A7
Amino acid transporter.
  
 
 0.567
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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