STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHAC1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (349 aa)    
Predicted Functional Partners:
TRIB3
Tribbles pseudokinase 3.
   
  
 0.882
ASNS
Asparagine synthetase [glutamine-hydrolyzing].
   
  
 0.832
PCK2
Phosphoenolpyruvate carboxykinase 2, mitochondrial.
   
  
 0.700
SESN2
Sestrin 2.
   
  
 0.700
ATF3
Activating transcription factor 3.
   
  
 0.640
ATF4
Activating transcription factor 4.
   
  
 0.627
TLR1
Toll like receptor 1; Belongs to the Toll-like receptor family.
      
 0.588
SERTAD1
SERTA domain containing 1.
   
  
 0.583
XBP1
BZIP domain-containing protein.
   
  
 0.565
ANTXRL
ANTXR like.
      
 0.561
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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