node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APBB3 | TP53INP1 | ENSCAFP00000008731 | ENSCAFP00000013869 | Amyloid beta precursor protein binding family B member 3. | Tumor protein p53 inducible nuclear protein 1. | 0.487 |
HIPK2 | PIN1 | ENSCAFP00000006003 | ENSCAFP00000026537 | Homeodomain interacting protein kinase 2. | Peptidyl-prolyl cis-trans isomerase. | 0.919 |
HIPK2 | TP53 | ENSCAFP00000006003 | ENSCAFP00000064590 | Homeodomain interacting protein kinase 2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.987 |
HIPK2 | TP53INP1 | ENSCAFP00000006003 | ENSCAFP00000013869 | Homeodomain interacting protein kinase 2. | Tumor protein p53 inducible nuclear protein 1. | 0.694 |
JMY | TP53 | ENSCAFP00000013312 | ENSCAFP00000064590 | Junction mediating and regulatory protein, p53 cofactor. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.492 |
JMY | TP53INP1 | ENSCAFP00000013312 | ENSCAFP00000013869 | Junction mediating and regulatory protein, p53 cofactor. | Tumor protein p53 inducible nuclear protein 1. | 0.591 |
LURAP1 | MKNK1 | ENSCAFP00000006363 | ENSCAFP00000006248 | Leucine rich adaptor protein 1. | MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. | 0.681 |
LURAP1 | TP53INP1 | ENSCAFP00000006363 | ENSCAFP00000013869 | Leucine rich adaptor protein 1. | Tumor protein p53 inducible nuclear protein 1. | 0.523 |
MKNK1 | LURAP1 | ENSCAFP00000006248 | ENSCAFP00000006363 | MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. | Leucine rich adaptor protein 1. | 0.681 |
MKNK1 | TP53INP1 | ENSCAFP00000006248 | ENSCAFP00000013869 | MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. | Tumor protein p53 inducible nuclear protein 1. | 0.501 |
MKNK1 | TTC39C | ENSCAFP00000006248 | ENSCAFP00000026836 | MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. | Tetratricopeptide repeat domain 39C. | 0.489 |
NUPR1 | TP53 | ENSCAFP00000025226 | ENSCAFP00000064590 | Nuclear protein 1, transcriptional regulator. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.487 |
NUPR1 | TP53INP1 | ENSCAFP00000025226 | ENSCAFP00000013869 | Nuclear protein 1, transcriptional regulator. | Tumor protein p53 inducible nuclear protein 1. | 0.691 |
PIN1 | HIPK2 | ENSCAFP00000026537 | ENSCAFP00000006003 | Peptidyl-prolyl cis-trans isomerase. | Homeodomain interacting protein kinase 2. | 0.919 |
PIN1 | TP53 | ENSCAFP00000026537 | ENSCAFP00000064590 | Peptidyl-prolyl cis-trans isomerase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.666 |
PIN1 | TP53INP1 | ENSCAFP00000026537 | ENSCAFP00000013869 | Peptidyl-prolyl cis-trans isomerase. | Tumor protein p53 inducible nuclear protein 1. | 0.499 |
TP53 | HIPK2 | ENSCAFP00000064590 | ENSCAFP00000006003 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Homeodomain interacting protein kinase 2. | 0.987 |
TP53 | JMY | ENSCAFP00000064590 | ENSCAFP00000013312 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Junction mediating and regulatory protein, p53 cofactor. | 0.492 |
TP53 | NUPR1 | ENSCAFP00000064590 | ENSCAFP00000025226 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Nuclear protein 1, transcriptional regulator. | 0.487 |
TP53 | PIN1 | ENSCAFP00000064590 | ENSCAFP00000026537 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Peptidyl-prolyl cis-trans isomerase. | 0.666 |