STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC39A14Solute carrier family 39 member 14. (490 aa)    
Predicted Functional Partners:
SLC39A8
Solute carrier family 39 member 8.
  
 
 
0.903
SLC30A10
Solute carrier family 30 member 10.
  
 
 0.741
SLC30A9
Solute carrier family 30 member 9.
  
  
 0.728
SLC4A7
Anion exchange protein.
   
 
 0.703
CNNM3
Cyclin and CBS domain divalent metal cation transport mediator 4.
     
 0.684
SLC39A1
Solute carrier family 39 member 1.
   
 
 0.678
ANO6
Anoctamin.
   
  
 0.647
SLC22A15
Solute carrier family 22 member 15.
      
 0.642
DNAJB11
DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1.
   
  
 0.601
SLC11A2
Solute carrier family 11 member 2.
  
  
 0.592
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.