STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPN13Protein tyrosine phosphatase non-receptor type 13. (2495 aa)    
Predicted Functional Partners:
PLEKHA2
Pleckstrin homology domain containing A2.
    
 0.914
PLEKHA1
Pleckstrin homology domain containing A1.
   
  0.907
FAS
Fas cell surface death receptor.
    
 
 0.806
APC
APC regulator of WNT signaling pathway.
   
 
 0.790
RAPGEF6
Uncharacterized protein.
    
   0.769
ENSCAFP00000062374
IF rod domain-containing protein; Belongs to the intermediate filament family.
    
 
 0.738
GAB1
GRB2 associated binding protein 1.
    
 0.705
PDLIM4
PDZ and LIM domain 4.
    
 
 0.704
TRIP6
Thyroid hormone receptor interactor 6.
    
 
 0.683
EFNB1
Ephrin B1.
    
 
 0.670
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.