STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALX4ALX homeobox 4. (414 aa)    
Predicted Functional Partners:
NEURL2
Neuralized E3 ubiquitin protein ligase 2.
   
  
 0.705
EXT2
Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.
      
 0.696
PHIP
Pleckstrin homology domain interacting protein.
    
 
 0.687
CTIF
Cap binding complex dependent translation initiation factor.
      
 0.671
TSPAN4
Tetraspanin.
   
  
 0.671
IRAK1BP1
Interleukin 1 receptor associated kinase 1 binding protein 1.
      
 0.659
PPFIA2
PTPRF interacting protein alpha 2.
      
 0.605
GTF2A1
General transcription factor IIA subunit 1.
      
 0.601
POLR2F
RNA polymerase II subunit F.
   
 
 0.588
SPATA25
Spermatogenesis associated 25.
      
 0.587
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.