STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GOT1Aspartate aminotransferase. (413 aa)    
Predicted Functional Partners:
MDH1
Malate dehydrogenase.
   
 0.979
MDH2-2
Malate dehydrogenase.
   
 0.974
GOT2
Aspartate aminotransferase.
  
0.973
MPST
Mercaptopyruvate sulfurtransferase.
  
 
 0.969
ENSCAFP00000047270
Ldh_1_N domain-containing protein.
   
 0.966
ENSCAFP00000062047
Ldh_1_N domain-containing protein.
   
 0.966
LDHC
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.964
LDHA
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.961
SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
   
 0.961
TST
Sulfurtransferase.
  
 
 0.960
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.